MALVERN, Pa., Jan. 21, 2014 (GLOBE NEWSWIRE) -- TetraLogic Pharmaceuticals Corporation (Nasdaq:TLOG) today announced that it has entered into a research collaboration with the Walter and Eliza Hall Institute of Medical Research to examine TetraLogic's SMAC-Mimetic birinapant in viral infections. Preclinical studies performed at the WEHI have indicated that SMAC-Mimetics decrease the viral burden in mice with human Hepatitis B Virus (HBV) by inducing apoptosis of virally infected hepatocytes while sparing the non-infected cells.
TetraLogic has entered into a license agreement with WEHI for worldwide exclusive rights to a patent application filed by the institute relating to a method of treating intracellular infections involving the administration of an Inhibitor of Apoptosis (IAP) antagonist.
"Our work with TetraLogic, if successful, will provide a truly novel approach," said Professor Douglas Hilton, Director, WEHI. "This is further evidence of our commitment to perform research that has a direct impact on the lives of patients."
"We are very excited about this collaboration and look forward to further progress in the research program with WEHI," said Mr. Kevin Buchi, CEO of TetraLogic. "This is an opportunity to build on pioneering basic research to attack infectious disease with a completely novel therapeutic approach."
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Read more: http://ir.tetralogicpharma.com/releasedetail.cfm?ReleaseID=820211
TetraLogic Announces Licensing and Research Collaboration With Walter and Eliza Hall Institute of Medical Research